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MicroSource Discovery Systems
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AnalytiCon Discovery GmbH
compound libraries comprising of fda-approved drugs, synthetic and semi-synthetic natural products as well as bioactives ![]() Compound Libraries Comprising Of Fda Approved Drugs, Synthetic And Semi Synthetic Natural Products As Well As Bioactives, supplied by AnalytiCon Discovery GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/compound libraries comprising of fda-approved drugs, synthetic and semi-synthetic natural products as well as bioactives/product/AnalytiCon Discovery GmbH Average 90 stars, based on 1 article reviews
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Biomol GmbH
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MicroSource Discovery Systems
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Image Search Results
Journal: Frontiers in Pharmacology
Article Title: In Vivo Dopamine Neuron Imaging-Based Small Molecule Screen Identifies Novel Neuroprotective Compounds and Targets
doi: 10.3389/fphar.2022.837756
Figure Lengend Snippet: Top 30 hit compounds from the bioactive high throughput screen with high SSMD and BHS (ranked by BHS).
Article Snippet: A total of 1,403
Techniques: High Throughput Screening Assay, Activation Assay
Journal: Memórias do Instituto Oswaldo Cruz
Article Title: Past and future of trypanosomatids high-throughput phenotypic screening
doi: 10.1590/0074-02760210402
Figure Lengend Snippet: HCS-based assays employed in trypanosomatid drug discovery
Article Snippet: , L. donovani , Laboratory strain: MHOM/SD/62/1S-cl2D , Intracellular amastigotes , None , Human acute monocytic leukemia (THP-1) cells , Number of host cells (cytotoxicity evaluation) and number of amastigotes per cell , Parasites kDNA and cell nucleus detected by DAPI. Cell boundary was delineated around the nucleus object. ,
Techniques: Infection, Immunostaining, Cytotoxicity Assay, Activity Assay, Luciferase, Proliferation Assay, Imaging, Time-Kill Assay, Derivative Assay, Expressing, Drug discovery, Staining, Labeling, SYBR Green Assay
Journal: International Journal of Molecular Sciences
Article Title: Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation
doi: 10.3390/ijms21249557
Figure Lengend Snippet: High-throughput screening performance of bioactive compounds in hiPSC-Hep. ( A ) Integrated spot signal (ISS) vs. valid cell count in 2D scatter plot for hiPSC-Hep seeded at 24K (green, Z’ = 0.38), 30K (pink, Z’ = 0.57) and 36K (blue, Z’ = 0.62) per well cell densities. Average of TG/FA treated wells (green squares) and average of BSA-treated cells (blue dots) per screening plate for ( B ) ISS relative values of BODIPY 493/503 fluorescence imaged in the green channel and ( C ) valid cell count relative to values of Hoechst 33342 fluorescence detected in the blue channel. Each data point represents the mean relative ISS from six fields per well and the average of 16 wells per plate. ( D ) Determined Z’ scores (dark green line) and robust Z’ scores (RZ’ light green line) calculation for ISS values in TG/FA vs. BSA treated controls per assay plate.
Article Snippet: We collaborated with
Techniques: High Throughput Screening Assay, Cell Counting, Fluorescence